Track 23: Pharmaceutical Nanotechnology
Introduction
The study of extremely small structures is known as nanotechnology. Pharmaceutical nanotechnology is concerned with the construction and development of small structures, such as atoms, molecules, or compounds, with sizes ranging from 0.1 to 100 nm into structures that can then be further developed into unique devices with desired features.
Nanotechnology's use in pharmaceutics facilitates the development of more sophisticated drug delivery methods, making it a valuable and effective tool to replace conventional dosage forms. The future of the pharmaceutical industry will be drastically altered by the specialist discipline of pharmaceutical nanotechnology. Pharmaceutical nanotechnology aids in the prevention and treatment of a number of diseases by identifying disease-related antigens as well as the microbes and viruses that cause the diseases.
Pharmaceutical nanotechnology has been crucial in overcoming a number of problems with traditional dose forms including tablets and capsules. Pharmaceutical nanotechnology was used to address the shortcomings of conventional forms, such as inadequate bioavailability, poor patient compliance, injury to healthy cells, etc.
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Pharmaceutical Nano Systems
Pharmaceutical nano systems include:
- polymeric nanoparticles, which range in size from 10 to 1000 nm and are completely drug-protective due to their biocompatibility and biodegradability. Polymeric nanoparticles are employed as drug delivery systems to deliver medications over an extended period of time.
- Dendrimers: Controlled polymerization results in dendrimers, which have a size of about 10 nm. These monodisperse polymeric structures are extremely branched. Dendrimers are employed for targeted medication delivery to macrophages and the liver as well as for regulated drug delivery.
- Metallic nanoparticles: Gold and silver colloids with a size of less than 100 nm are considered metallic nanoparticles. They are incredibly tiny, which increases their surface area, bioavailability, and stability—all qualities that make a medicine desirable. These are employed in sensitive diagnostic assays, thermal ablation, and radiation augmentation, as well as medication and gene delivery.
- Polymeric micelles: These have a size range of 10-100 nm and are highly biocompatible and drug-entrapping in nature. These are utilised for both active and passive targeted medication delivery and have a high diagnostic vatu.
- Liposomes: These phospholipid vesicles, which range in size from 50 to 100 nm, have high entrapment efficiency and good biocompatibility. These are employed for both passive and active gene, protein, and peptide delivery.
Nanomaterials for pharmaceutical use
The following materials are among the many that are crucial to pharmaceutical nanotechnology:
Nanomaterials: These are biomaterials that are utilised to coat or modify the surfaces of different other materials, improving their biocompatibility and bioavailability.
Nanocrystalline materials: These are produced to serve as replacements for substances with subpar bioavailability, solubility, etc.
Nanostructured materials: These are refined forms with unique properties, such as microfluidics, microarrays, and nano- and micro-electromechanical systems.
Pharmaceutical nanotechnology applications
Drug administration methods: Standard drug delivery methods have a number of drawbacks, including a lack of specificity, a high rate of drug metabolism, cytotoxicity, a need for high doses, poor patient compliance, etc.
and by creating drug delivery systems employing the fundamentals of pharmaceutical nanotechnology, these obstacles can be removed.
In order to characterise and quantify biological processes in organisms, such as gene expression, protein-protein interactions, signal transduction, cellular metabolism, and both intracellular and intercellular trafficking, molecular imaging is a science.
Drug development: Pharmaceutical nanotechnology is crucial to the development of new pharmaceuticals because it enhances the properties of powerful drugs and excipients, such as solubility and bioavailability.
Conclusion
A new field of study in pharmaceutical nanotechnology offers better chances in various areas of diagnosis and treatment. Pharmaceutical nanotechnology has emerged as a growing field of study with enormous potential as a delivery system for numerous powerful medications and diagnostics. Through its nanoengineered instruments, it is well known as a specialised field for medication administration, diagnostics, prognostication, and therapy of disorders. It offers the chance to enhance materials, medical equipment, support the creation of new technologies, and get around the constraints of traditional methods.
List of Pharma Association
List of Pharma Society
- International Society for Pharmaceutical Engineering
- Royal Pharmaceutical Society
- Society of Pharmaceutical Education & Research
- Pharmaceutical Society of Australia
- Royal Pharmaceutical Society
- Pharma Society (PSOLATE)
- The Pharmaceutical Society of Japan
- Pharmaceutical Society of New Zealand
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Subtopics Of Biosimilars
Nanoparticles for drug delivery
Advances and challenges of nanotechnology
Cell culture models and nanobiotechnology
Evaluating Nanoparticles in Preclinical Research